关节突关节方向与退行性腰椎滑脱关系的研究进展

Research progress on the relationship between facet joints orientation and degenerative lumbar spondylolisthesis

关键词:  关节突关节  退行性腰椎滑脱  关节突关节方向  发病机制

Key words:  facet joint  degenerative lumbar spondylolisthesis  facet joint orientation  pathogenesis

摘要:

退行性腰椎滑脱（degenerative lumbar spondylolisthesis，DLS）是指在脊柱退变基础上，整个上位椎体 （椎体和椎体后部，包括椎弓根和关节突关节）相对于下位椎体出现的滑移的疾病。目前，在临床上DLS是导致中 老年人出现腰腿痛的常见疾病。但其发病机制尚未明了，特别是关节突关节方向的改变在退行性椎体滑移发病机 制中的作用一直存在争议。因此，该文阐述了关节突关节方向的改变与退行性腰椎滑脱之间因果关系的研究进展。

Abstract:

Degenerative lumbar spondylolisthesis (DLS) refers to a disease in which the entire upper vertebral body (vertebral body and posterior part of vertebral body, including pedicle and facet joints) slides relative to the lower vertebral body on the basis of spinal degeneration. Currently, DLS is also a prevalent clinical condition that causes lower back and leg pain in middle-aged and elderly people. With the aging of our society, especially the increasing number of middle-aged and elderly people suffering from degenerative lumbar spondylolisthesis, this condition has caused a huge medical burden on our society. It is imperative to study the risk factors and pathogenesis of lumbar spondylolisthesis. However, its pathogenesis remians unclear, and especially, the role of changes in the facet joint orientation in the pathogenesis of degenerative vertebral slip has been controversial. This article provides a review of the research progress on the causal relationship between changes in the facet joint orientation and degenerative lumbar spondylolisthesis.