引用本文:杨欣欣 1,2,何月敬 3,等.脂肪因子PAMM的生物学功能及其临床应用前景[J].广东医科大学学报,2024,42(1):93-98.[点击复制]
【打印本页】 【下载PDF全文】 【HTML】

←前一篇|后一篇→

过刊浏览    高级检索

本文已被:浏览 465次   下载 264 本文二维码信息
码上扫一扫!
脂肪因子PAMM的生物学功能及其临床应用前景
杨欣欣1,2,何月敬3,马佳仪1,2,叶轩轩1,2,史玉仓4,徐明锋5,梁 杰4,吴志远4,孙雪荣1*
0
(1. 广东 医科大学广东省医学分子诊断重点实验室衰老研究所,广东东莞 523808;2. 广东医科大学第二临床医学院,广东 东莞 523808;3. 东莞市第八人民医院临床检验科,广东东莞 523321;4. 广东医科大学附属医院整形外科,广东 湛江 524001;5. 广东医科大学生理学教研室,广东湛江 524023)
摘要:
PAMM(Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes)是一种氧化还原调节蛋白,在脂肪组 织中高表达,具有广泛的生物学作用,是脊髓损伤的标志物及某些肿瘤治疗的候选靶点。该文就PAMM的生物学功能及 其临床应用前景作一综述。
关键词:  PAMM  脂肪因子  抗氧化
DOI:
基金项目:广东省自然科学基金(2021A1515012236),广东医科大学附属医院“临床医学+”科技合作项目(CLP2021B011),广东医 科大学学科建设类“临床+基础”专项项目(4SG23287G)
Biological function and potential application of adipocytokine PAMM
YANG Xin-xin1,2, HE Yue-jing3 , MA Jia-yi1,2, YE Xuan-xuan1,2, SHI Yu-cang4 , XU Ming-feng5 , LIANG Jie4 , WU Zhiyuan4 , SUN Xue-rong1*
(1. Institute of Aging Research, Guangdong Provincial Key Laboratory of Medical Molecular Diagnostics, Guangdong Medical University, Dongguan 523808, China; 2. The Second Clinical Medical School, Guangdong Medical University, Dongguan 523808, China; 3. Clinical Laboratory, Dongguan Eighth People’s Hospital, Dongguan 523321, China; 4. Department of Plastic Surgery, Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China; 5. Department of Physiology, Guangdong Medical University, Zhanjiang 524023, China)
Abstract:
PAMM (Peroxiredoxin-like 2 activated in M-CSF stimulated monocytes) is a redox-regulated protein that is highly expressed in adipose tissue, and has various biological roles. It can serve as a biomarker for spinal cord injury and a candidate target for certain tumors. This paper reviews the biological function and potential application of PAMM.
Key words:  PAMM  adipocytokine  antioxidation

用微信扫一扫

用微信扫一扫