| 摘要: |
| 中晚期肝细胞癌（HCC）的治疗以非手术治疗为主，如何制定个性化的治疗方案或根据疗效及时调整方案是目前临床急需解决的关键问题，因此，早期准确地评估中晚期HCC的治疗效果尤为重要。目前，公认的主要评估方式是增强CT和增强MRI，但是CT具有辐射性，不适合反复多次检查；MRI价格昂贵、部分患者检查受限。超声造影（CEUS）能实时、动态、无辐射、高敏感性地识别肿瘤的活性。该文综述了CEUS在中晚期HCC非手术治疗效果评估中的应用研究现状。 |
| 关键词: 肝细胞癌 , 非手术治疗 , 效果 , 超声造影 |
| DOI： |
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| 基金项目:广东医科大学科研基金立项资助项目（GDMUM2020033） |
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| Current study of contrasted-enhanced ultrasound in the assessment of the effectiveness of non- surgical treatment of middle and advanced hepatocellular carcinoma |
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| Abstract: |
| Non-surgical modalities was widely used in the treatment of middle and advanced hepatocellular carcinoma (HCC). Thus, how to enact a personalized treatment plan or adjust the plan in time according to the efficacy is a key issue that needs to be urgently solved in the clinic nowadays, so it is especially important to accurately assess the efficacy of the treatment of middle and advanced HCC at an early stage. At present, enhanced computed tomography (CT) and enhanced magnetic resonance imaging (MRI) are the main assessment modalities. , However, CT is radioactive and not suitable for repeated examinations while theMRI is expensive and limited for patients. Contrast-enhanced ultrasound (CEUS) has been considered a better way to detect the tumors with high sensitivity and dynamic and without radiation. We summarized the current research advances of ultrasonography in the evaluation of the efficacy of non-surgical treatment of middle and advanced HCC. |
| Key words: hepatocellular carcinoma non-operative treatment efficacy contrasted-enhanced ultrasound |