| 摘要: |
| 摘 要：肿瘤的发生发展与机体的免疫状态、营养状态及肿瘤微环境息息相关，一些传统的评估方法对肿瘤的预后
评价效果已略显不足，这可能与它们仅基于肿瘤的形态学特征而未考虑机体免疫营养状态有关。近年，在对肿瘤预后评
估的领域出现了一种新的评分系统，即Gustave Roussy Immune Score（GRIm-Score）。该文通过梳理近年来应用该评分系
统的文献，回顾了该评分在常见消化系统恶性肿瘤患者预后评估中的应用，认为GRIm-Score是多种常见消化系统恶性肿
瘤预后的独立危险因素，高评分往往提示预后不良，且可能与免疫抑制剂治疗效果评估也有一定相关性。 |
| 关键词: 消化系统恶性肿瘤 GRIm-Score 炎症 营养 预后 综述文献 |
| DOI： |
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| 基金项目:2019 年度广东医科大学附属医院院内资助类临床研究项目（LCYJ2019B007），2021 年度湛江市科技发展专项资金竞争 性分配项目（2021A05080），2020 年度广东省医学科研基金立项项目（B2020112） |
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| Research progress of Gustave Roussy Immune Score in prognosis assessment of patients with malignant tumors of digestive system |
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| Abstract: |
| Abstract: Tumor development and progression are closely related to the immune state, nutritional state, and tumor
microenvironment. Traditional evaluation methods have been slightly insufficient in evaluating the prognosis of tumors, which
mainly focus on the morphological characteristics of tumors instead of the immune nutritional state .Therefore, Gustave Roussy
Immune Score (GRIm-Score), which is considered as new way to evaluate the tumor prognosis has been proposed in recent
years. In this paper, we summarize recent application of this scoring system in prognosis assessment of patients with common
digestive system malignant tumors and demonstrated that GRIm-Score is an independent risk factor for the prognosis of a
variety of common digestive system malignancies, and high score often indicates poor prognosis, and may also have a certain
correlation with the evaluation of immunosuppressive therapy effect. |
| Key words: malignant tumor of digestive system GRIm-Score inflammation nutrition prognosis review |