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NLR、PLR、SII、LMR、CRP在乳腺癌患者血清中表达意义的研究进展
滕玥玥,黄妙君,黄胜超,李建文,张远起
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摘要:
摘 要:乳腺癌是女性最为常见的恶性肿瘤之一,每年新发病例仍在不断增加。由炎性细胞所控制的肿瘤微环境已 被证明与乳腺癌的发展、转移及预后显著相关。该文就常见的外周血炎症指标性粒细胞/淋巴细胞比值、血小板/淋巴细 胞比值、系统免疫炎症指数、淋巴细胞/单核细胞比值及C反应蛋白在乳腺癌发生发展、预后及疗效预测中的应用研究进 展作一综述。
关键词:  乳腺癌  中性粒细胞/淋巴细胞比值  血小板/淋巴细胞比值  系统免疫炎症指数  淋巴细胞/单核细胞比值  C反应蛋白
DOI:
基金项目:广东省普通高校特色创新类项目(2021KTSCX037),吴阶平基金(320-6750-2021-10-35),广东医科大学附属医院竞争性 临床研究(LCYJ2021B003),广东医科大学附属医院临床医学(CLP2021B002),湛江市科技发展专项资金竞争性分配项 目(2022A01190)
Advances in the application of serum NLR, PLR, SII, LMR and CRP in breast cancer
()
Abstract:
Abstract: Breast cancer is one of the most common malignant tumors in women, with the number of new cases increasing every year. The tumor microenvironment controlled by inflammatory cells has been proved to be significantly associated with the progression, metastasis and prognosis of breast cancer. This paper reviewed the advance in the application of peripheral blood inflammatory indexes, such as granulocyte/lymphocyte ratio, platelet/lymphocyte ratio, systemic immune inflammatory index, lymphocyte/monocyte ratio and C-reactive protein in the prediction of the occurrence, progression, prognosis and therapeutic efficacy of breast cancer.
Key words:  breast cancer  neutrophil/lymphocyte ratio  platelet/lymphocyte ratio  systemic immunoinflammatory index  lymphocyte/monocyte ratio  C-reactive protein

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