维生素A、C、D以及E缓解过敏性疾病的研究进展

Progress of four kinds vitamins A, C, D, and E in alleviating allergic diseases

摘要:

过敏是机体对环境中普遍存在的物质产生异常的一种免疫反应，是一个全球性的公共卫生问题。维 生素是一类小分子有机化合物，是机体必需的营养素之一，对人体的生长发育、新陈代谢和健康起着重要作用。众 多研究表明，补充维生素有助于缓解过敏症状。该文综述了4种维生素A、C、D以及E对过敏性疾病的影响，其中， 维生素A通过调节免疫细胞分化和抑制Th2型免疫反应缓解过敏；维生素C凭借其抗氧化特性，抑制炎症信号通路 激活，减少过敏介质释放；维生素 D可调节 Th17/Treg平衡，抑制 IgE生成；维生素 E则通过抗氧化作用抑制促炎细 胞因子产生，减轻过敏症状。该文旨在为预防和缓解某些过敏性疾病提供理论参考和新思路。

Abstract:

Allergy is an abnormal immune response to substances in the environment, and it is also a public health disease. Vitamins, essential small organic molecules for the human body, are crucial for growth, development, metabolism, and overall health. Studies have shown that supplementing with certain vitamins can help ease allergy symptoms. In this paper, the effects of vitamins A, C, D, and E on allergic diseases were reviewed. Vitamin A alleviates allergies by regulating immune cell differentiation and inhibiting Th2-type immune responses; Vitamin C, with its antioxidant properties, suppresses the activation of inflammatory signaling pathways and reduces the release of allergic mediators; Vitamin D modulates immune responses by balancing Th17/Treg cells and suppressing IgE production; And vitamin E mitigates allergy symptoms via its antioxidant effects, thereby can inhibit pro-inflammatory cytokine production. The purpose of this review is to provide theoretical references and new ideas for the prevention and alleviation of certain allergic diseases.