DXA、QCT、DECT应用于骨质疏松性椎体压缩性骨折内固定治疗的研究进展

Advance in the application of DXA, QCT, and DECT in the internal fixation treatment of osteoporotic vertebral compression fractures

摘要:

骨质疏松性椎体压缩性骨折（OVCFs）是一种中老年人常见的骨骼疾病，严重影响患者的生活质量和健康。在不稳定型OVCFs的治疗中，椎弓根螺钉内固定术能为椎体提供强力有效的支持，已成为重要的手术选择。然而，严重的骨质疏松会使内固定治疗失效率高。准确测量患者的骨密度评估骨质疏松情况对于手术成功和临床结果有较大影响。目前最常用的骨密度评估技术有双能X射线吸收法（DXA）、定量计算机断层扫描（QCT）和双能量CT（DECT）。该文综述了此 3 种技术在OVCFs的应用状况及优劣势的研究进展。

Abstract:

Osteoporotic vertebral compression fractures (OVCFs) are common skeletal disorders in the middle aged and elderly people, significantly affecting their quality of life and overall health. Among the treatments for unstable OVCFs, pedicle screw fixation can offer robust and effective support to the vertebral body and has become a crucial surgical option. However,severe osteoporosis can lead to a high failure rate of internal fixation treatment. Hence, the accurate measurement of a patient’s bone density to assess osteoporotic conditions has great influence on surgical success and clinical outcomes. Currently, the most commonly used bone density assessment techniques include dual-energy x-ray absorptiometry (DXA), quantitative computed tomography (QCT), and dual-energy CT (DECT). This paper reviewed the application of these three techniques in OVCFs and the advantages and disadvantages thereof.