Abstract:Objective To explore the clinical efficacy of negative pressure drainage applied to inguinal hernia patients taking antithrombotic drugs for a long time. Methods 63 surgical patients on long-term antithrombotic medication were randomly divided into study group (negative pressure drainage) and control group (no negative pressure drainage ).The operation time, bleeding volume, hospital stay, time of the first postoperative out-of-bed activity, visual acuity of pain in postoperative day 1 and 3 in the 2 groups were compared. analogue score (VAS), postoperative complications (surgical incision infection, fatty liquefaction, subcutaneous haematoma, seroma, scrotal effusion, thrombosis), and the amount of drains were recorded. Results The hospitalisation time and the first postoperative time to get out of bed of the patients in the study group were shorter than those in the control group(P<0.01 or 0.05); the incidence of postoperative complications was lower than that in the control group(P<0.01). Conclusion Negative pressure drainage has safe and feasible clinical efficacy for patients with inguinal hernia who have been taking antithrombotic drugs for a long time, and it is worth to promote its use.