Abstract:Objective To investigate the predictive value of ferritin, uric acid, homocysteine (Hcy), and hypersensitive C-reactive protein (hs-CRP) for carotid intima-media thickening (CIMT) in primary hypertension. Methods A total of 106 patients with primary hypertension were divided into thickening group (55 cases) and normal group (51 cases). Ferritin, uric acid, Hcy, and hs-CRP levels were compared between 2 groups and analyzed Logistic regression analysis. Their predictive value for CIMT was evaluated using ROC curve. Results Ferritin, uric acid, Hcy, and hs-CRP levels were higher in thickening group than in normal group (P<0.01). Logistic regression analysis showed that they were independent risk factors for CIMT (P<0.05). The AUC of ferritin, uric acid, Hcy, hs-CRP, and their combination were 0.735, 0.802, 0.818, 0.778, and 0.939 (P<0.01), respectively. Conclusion There may be some predictive value of ferritin, uric acid, Hcy, and hs-CRP for CIMT in primary hypertension, with the highest of their combined detection.