多胺代谢在调控肿瘤血管生成中作用机制的研究进展

Research progress of polyamine metabolism in functional regulating tumor angiogenesis

摘要:

摘 要：多胺（PA）是普遍存在于动植物所有组织和细胞类型中的脂族聚阳离子，与肿瘤的血管生成密切相关。该文 就多胺代谢与肿瘤血管生成的关系及机制的研究进展进行综述，以期为靶向多胺代谢的临床抗肿瘤血管生成治疗提供 新的理论依据。

Abstract:

Abstract: Polyamines are aliphatic polymeric cations commonly present in all tissues and cell types of animals and plants and polyamine metabolism is closely related to angiogenesis in tumors. This review summarize the research progress on the relationship and mechanism by which polyamine metabolism regulate tumor angiogenesis, providing polyamine metabolism is new target in tumor angiogenesis.