54 例孕妇超前分娩镇痛的有效性和安全性观察

Observation of the effectiveness and safety of preemptive labor analgesia in 54 pregnant women

摘要:

目的 观察超前镇痛用于孕妇超前分娩镇痛的有效性和安全性。方法 108 例孕妇随机分为对照组和超 前镇痛组，每组 54 例。对照组：采用硬膜外注入罗哌卡因+舒芬太尼混合液进行自控麻醉镇痛（PCEA）。超前镇痛组： 孕妇即将进入临产、未规律宫缩前泵入 1 mL/h镇痛药（包括 1.2 g/L罗哌卡因、0.4 mg/L舒芬太尼），进入规律宫缩后进行 PCEA。比较两组镇痛效果、麻醉药物用量、分娩方式、孕妇满意度以及不良反应。结果 超前镇痛组的镇痛有效率、孕妇 满意度均明显高于对照组，剖宫产率低于对照组（P<0.05）。两组孕妇麻醉药物用量、不良反应发生率差异无统计学意义 （P>0.05）。结论 超前镇痛用于分娩镇痛可以有效提高镇痛效果和孕妇满意度，降低剖宫产率。

Abstract:

Objective To observe the effectiveness and safety of preemptive labor analgesia in pregnant women. Methods A total of 108 pregnant women were randomly divided into the Preemptive Analgesia Group and the Control Group, 54 cases in each group. The Control Group received epidural injection of a mixture of ropivacaine + sufentanil for patient-controlled epidural analgesia (PCEA) while the Preemptive Analgesia Group received the pumping of 1 mL/h of analgesics (including 1.2 g /L ropivacaine and 0.4 mg/L sufentanil) before they were about to labor and had irregular contractions and received PCEA after having regular contractions. The analgesic effect, anesthetic dosage, delivery mode, pregnant women’s satisfaction and adverse reactions were compared between the two groups. Results The effective rate of analgesia and the satisfaction of pregnant women in the Preemptive Analgesia Group were significantly higher than those in the Control Group, and the cesarean section rate in the Preemptive Analgesia Group was lower than that in the Control Group (P<0.05). There were no significant differences in the anesthetic dosage and the incidence of adverse reactions between the two groups (P>0.05). Conclusion Preemptive labor analgesia can effectively improve the analgesic effect and pregnant women’s satisfaction and reduce the cesarean section rate.