| 摘要: |
| 摘 要：目的 利用多导睡眠监测（PSG）分析多系统萎缩（MSA）患者的睡眠障碍。方法 6 例MSA患者和 6 例对
照者进行PSG监测，比较两组总睡眠时间、睡眠效率、睡眠潜伏期、入睡后清醒时间、觉醒次数、各睡眠分期占比、微觉醒
指数、呼吸暂停低通气指数（AHI）、睡眠周期性肢体运动指数（PLMSI）等指标。结果 MSA患者总睡眠时间和睡眠效率
低于对照组（P<0.01）；入睡后清醒时间、浅睡眠N1 期比例、微觉醒指数、AHI、PLMSI均高于对照组（P<0.01 或 0.05）。
5 例MSA患者出现快动眼睡眠肌张力失迟缓（RSWA），4 例出现喘鸣，2 例出现大喊大叫及拳打脚踢现象。结论 MSA
患者存在较严重睡眠障碍。 |
| 关键词: 多系统萎缩 睡眠障碍 多导睡眠监测 |
| DOI： |
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| 基金项目:：湖南省自然科学基金科卫联合项目（2021JJ70124），长沙市卫生健康委科研计划项目（KJ-B2023048） |
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| Application of polysomnography in patients with multiple system atrophy and somnipathy |
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| Abstract: |
| Abstract: Objective To study the somnipathy in patients with multiple system atrophy (MSA) using polysomnography
(PSG). Methods Six MSA patients and 6 healthy controls underwent PSG. Total sleep time, sleep efficiency, sleep latency,
wake after sleep onset (WASO), awaking times, sleep stages, microarousal index, apnea-hypopnea index (AHI), and periodic
limb movement of sleep index (PLMSI) were compared between two groups. Results Compared with control group, total
sleep time and sleep efficiency were lower (P<0.01), while WASO, N1 light sleep, microarousal index, AHI, and PLMSI were
higher in control group (P<0.01 or 0.05). In addition, REM sleep dystonia, stridor and disturbed episodes occurred in 5, 4 and 2
MSA patients. Conclusion There is a severe somnipathy in MSA patients. |
| Key words: multiple system atrophy somnipathy polysomnography |